We are please to provide the following community statement that has just been released by Ionis about their upcoming clinical trial.
Ionis prion community update - October 2023 - final
John Collinge (MRC Prion Unit, University College London, London, UK) discusses a first-in-human treatment programme to give PRN100, an anti-prion-protein monoclonal antibody, to patients with Creutzfeldt–Jakob disease; the report is published in the April issue of The Lancet Neurology.
In Conversation with… John Collinge (link to podcast with listing options)
A comparison of Granagard and Metformin as ageing hallmarks in the Tg E200K model.
Here is your chance to help towards a treatment or cure for prion disease. Ionis Pharmaceuticals, a company based in Carlsbad, California US that develops antisense drugs targeting the RNA. In the past, Ionis has successfully developed antisense drugs that treat diseases such as Spinal Muscular Atrophy and TTR Amyloidosis. they are working on doing the same for prion disease.
They are currently undertaking a survey on genetic testing for prion diseases (PRNP testing) and we ask anyone from a genetic prion disease family or anyone who has undergone or considered genetic testing for prion disease to please complete the survey provided in the link below.
Your help would be very much appreciated.